International Journal of Advanced Multidisciplinary Research and Studies
Volume 2, Issue 1, 2022
Antipsychotic activity of herbal plants: A review
Author(s): Siddique Nadim, Ansari Mubark, Dr. Srivastava Amit Kishore, Dr. Verma Neeraj, Dr. Gupta Amresh
Abstract:
Mental illness, a crucial mutual health problem, is a chronic frequent neuropsychiatric disorder that adversely affects the quality of life of the patient. About 1% of the world population is affected by a chronic debilitating neuropsychiatric disease i.e., Psychosis. Psychosis may be minor or major, major psychosis termed as schizophrenia. Schizophrenia is a severe neuropsychiatric disorder, characterized by disturbance in thinking which affects speech, perception and the sense of self. The one pharmacological property common by all available antipsychotics is blockade of the dopamine D2 receptor. Direct blockade of the D2 receptor and secondary depolarization blockade both appear relevant to antipsychotic action. Albizia zygia root extract, Viscum album L. (Loranthaceae), Desmodium adscendens, Synedrella nodiflora (L) Gaertn, Lonchocarpus cyanescens, Noni (Morinda citrifolia Linn.) are the plants which having antipsychotic effect. Some dietary supplement which also use full in the management of psychosis.
Keywords: Schizophrenia, Dopamine, Amphetamine, D2 Receptor, Antipsychotic
Pages: 80-83