International Journal of Advanced Multidisciplinary Research and Studies
Volume 5, Issue 2, 2025
Antibiotic Resistant Pattern of Bacteria Isolated from Effluent Discharge Points of Pharmaceutical Industries in Imo State Nigeria
Author(s): Chinyere Ohalete, Bede C Azudialu, Benjamin Nkem, Chiamaka Azudialu
Abstract:
Background
Antibiotic resistance of pharmaceutical effluent refers to the phenomenon where antibiotic resistant bacteria and antibiotic residues are present in the waste water discharged from pharmaceutical manufacturing facilities. The discharge of pharmaceutical effluent into the environment has significant impact on ecological systems and overall health of the environment.
Aim
The aim of this study is to investigate the antibiotic resistant patterns of bacteria isolated from effluent discharge points of pharmaceutical industries in Imo state, Nigeria.
Methods
Effluent discharges were collected from multiple discharge points of pharmaceutical facilities and bacteria isolates underwent antimicrobial susceptibility test against commonly used antibiotics.
Results
This study reveals a significant prevalence of antibiotic resistant bacteria, including multi-resistant strains in the pharmaceutical effluent. The presence of resistance to beta lactams, fluoroquinolones and tetracyclines suggest potential challenge in treating infectious diseases and raises concerns for public health.
Recommendations
These include improving waste water treatment processes, promoting responsible antibiotics use in the pharmaceutical industry, strengthening regulatory oversight, fostering collaboration among stakeholders. Urgent measures are needed to mitigate the risks associated with antibiotics resistance, safeguard public health and protect the environment in Imo State.
Keywords: Antibiotic Resistance, Pharmaceutical Industries, Effluent Discharges, Imo State
Pages: 1129-1132
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