Prevalence of Carbapenem resistant Pseudomonas aeruginosa at hospital in Baghdad, Iraq

Worldwide, Infections related to healthcare are frequently caused by multidrug resistant Pseudomonas aeruginosa, Gram-negative bacteria, such as Pseudomonas aeruginosa, that are resistant to many drugs produce infections that can be treated with carbapenems, although its use is threatened by the emergence of carbapenemase-producing strains. The aim of this study was to determine the prevalence of carbapenem resistant Pseudomonas aeruginosa In Baghdad hospitals, by conducting susceptibility test and identification of carpenemase genes harbored by the isolates. 125 samples were collected from various clinical sources, and 68 isolates of Pseudomonas aeruginosa showed. Susceptibility tests showed that 35 isolates were carbapenem-resistant. The carbapenemase genes blaOXA-48, blaKPC and blaVIM were found in 5.7%, 2.9% and 22.9%, respectively, and the blaOXA-48 and blaVIM genes were coexpressed in one isolate, blaIMP was not observed in the isolates. For the efficient treatment of carbapenem-resistant Pseudomonas aeruginosa infections, epidemiological and geographic evaluation of carbapenemase-producing Pseudomonas aeruginosa should be taken into consideration.