E ISSN: 2583-049X

International Journal of Advanced Multidisciplinary Research and Studies

Volume 3, Issue 5, 2023

Correlation Study between CCL2 and Cortisol in Men Patients Infected with Toxoplasmosis

Author(s): Zahraa Ali faieq, Saleem Khteer Al-Hadraawy


Toxoplasma gondii has a worldwide distribution and it is one of the most prevalent infectious agents in Iraq, as it is found in various mammals, fish, and terrestrial and water birds. Cats are the only definitive host for the parasite that throws the infective phase into the environment. The primary aim of this study was to determine the serum levels of CCL2 and cortisol in patients and healthy groups. The study was conducted on 260 Males suspected of Toxoplasmosis ages ranging from 20-50 years old. All these cases were examined by measuring Toxo IgM and IgG serum levels, who attended AL-Hakeem hospital, and (30) healthy males as the control group, collected randomly from AL-Najaf province, these samples were collected from March 2023 to August 2023. Any patient was using the drug or undergoing disease removal from the current study. The current study revealed that the concentration of (CCL2 and cortisol) in patients infected with Toxoplasmosis had a significant increase (P  compared to the control group. Also, the current results revealed that the serum levels of CCL2 (ng/ml) correlated positively and significantly with cortisol (ng/ml) in patients infected with chronic Toxoplasmosis. The current study has concluded that infection with Toxoplasmosis may be a risk factor. A chronic T. gondii infection is associated with variations in levels of serum hormones for can result in inducted behavioural alterations and these variations may influence the immune system by Cortisol thus increasing the susceptibility to Toxoplasmosis infection.

Keywords: Kufa, Men, Toxoplasmosis, CCL2, Cortisol

Pages: 744-748

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