Phenotypic and Genotypic Study of Some Virulence Factors for Klebsiella Pneumonia Isolation from Diabetic Foot Ulcer and Urinary Tract Infection

The pathogenicity of K. pneumoniae bacteria is associated with several virulence factors that allow it to evade the host’s innate immune mechanisms. To establish infection, K. pneumoniae must overcome mechanical and chemical barriers and escape host humoral and cellular innate defenses. After gaining access to the host, the invading organisms are recognized by the immune cells. In this study, 42 K. pneumoniae clinical specimens isolated from diabetic patients whose suffering from urinary tract infection and diabetic foot ulcer. Present virulence factors of K.pneumoniae detect by phenotypic and genotypic methods. The K. pneumoniae isolates which were positive for various virulence factors were as follows on Slim layer 34(80.9%), Gelatinase 11(26.1%), Bioflim 41(97.6%), Lipase 0(0). The genotypic detection showed that K. pneu¬moniae had virulence genes and were 8(40%) for wabG and 8(40%) for fimH.