E ISSN: 2583-049X

International Journal of Advanced Multidisciplinary Research and Studies

Volume 3, Issue 2, 2023

Comparison of Prolene and Polydioxanone in Midline Closure

Author(s): Dr. Mubashir Hassan, Dr. Asif Khan, Dr. Nizam-ud-din, Dr. Ubaid Ullah, Dr. Adil Jan, Dr. Nasir Khattak, Dr. Amir Hamza Khan



To compare the frequency of post-operative wound infection with polydioxanone and prolene in midline closure in laparotomy.

Study Design:

Randomized Controlled Trial.


Department of Surgery, KTH, Peshawar.

Duration of Study:

This study was conducted from 1st May 2021 to 1st November 2021.

Subjects and Methods:

A total of 130 patients of both gender undergoing elective laparotomy with midline abdominal incisions were included in the study. Final assessment of wound infection was done on 30th postoperative day as per operational definition from both groups and noted.


Age range in this study was 18 to 50 years with mean age of 36.569±8.03 years and mean duration of procedure was 70.430±11.29 mins in Group A and mean age of 39.446±7.79 years and mean duration of procedure was 68.646±10.81 mins in Group B. Wound infection was observed in 2 (3.1%) patients in group A as compare to 11 (16.9%) patients in group B (P= 0.009).


Our study showed closure technique using Polydioxanone for closure of midline laparotomy incision is superior to prolene suture material in preventing wound infection.

Keywords: Laparotomy, Polydioxanone, Prolene, Wound Infection

Pages: 832-835

Download Full Article: Click Here