E ISSN: 2583-049X

International Journal of Advanced Multidisciplinary Research and Studies

Volume 3, Issue 3, 2023

To Determine the Diagnostic Accuracy of Raised Serum Bilirubin in Predicting Acute Appendicitis Taking Post-Operative Histopathology as the Gold Standard

Author(s): Dr. Maaz Bin Altaf, Dr. Asad Farooq, Dr. Muhammad Yasir Jan, Dr. Saad Ul Khaliq, Dr Athar Ahmad, Dr. Komal Qayyum, Dr. Warda Batool Nadeem



To determine the diagnostic accuracy of raised serum bilirubin in predicting acute appendicitis taking post-operative histopathology as the gold standard.

Study Design: Cross sectional Validation.

Study Duration: May 14, 2019 to Nov 13, 2019.

Material and Methods

After taking permission from the hospital ethical committee all the patients presenting with symptoms of abdominal pain that migrates to right iliac fossa, anorexia, nausea, vomiting, fever, tenderness in the right iliac fossa, rebound tenderness in the right iliac fossa and fulfilling the inclusion criteria were admitted in surgical unit through OPD and Emergency Department. Complete baseline investigations including total serum bilirubin were done prior to surgery and readings were noted. Post operatively the appendix specimen were collected, preserved in formaline solution and sent to a single expert histopathologist. The patient’s histopathology reports were followed up for in out patient department.

Results: 1

84 patients with suspected appendicitis had observed. Male to female ratio 1.19:1. Average age was 28.27 years+ 9.06SD. Majority of the appendicitis 124(67.39%) were confirm through histopathology while on 60(32.61%) were not confirmed as acute appencitis. Over all the diagnostic accuracy of serum belirubine in diagnosis of acute appendicitis is 80.98%.

Conclusion: Serum bilirubin can be considered as a vital tool for the diagnosis of acute appendicitis. In situations where this investigation is normal, further evaluation needs to be done in the form of an ultrasound or diagnostic laparoscopy.

Keywords: Acute Appendicitis, Serum Bilirubin, Appendicectomy, Sensitivity, Specificity

Pages: 473-477

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